Is there a decent real alternative to iTunes?

I don't like apple mail, i don't like safari, i don't like iworks, i don't like apple calendar, and apple contacts... and of course, i don't like itunes, specially the last version.

Therefore, the question is, is there a decent alternative to itunes? something that can use the keyboard volume keys and play and pause, and the macbook remote and that stuff.

and if it can sync with itunes library and even handle the ipod, would be awesome...